Protein Details: Aquaporin-2
Protein ID
ICDB_Pro_0697
Protein Name
Aquaporin-2
Gene Name
AQP2
Organism
Bos taurus (Bovine)
Length
271 amino acids
AlphaFoldDB
AF-P79099-F1-model_v4.pdb
Function
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water; thereby permitting water to move in the direction of an osmotic gradient.
Sequence
MWELRSIAFSRAVLAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAVFYVAAQLLGAVAGAALLHEITPPAIRGDLAVNALNNNSTAGQAVTVELFLTLQLVLCIFASTDERRGDNVGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAIVTGKFDDHWVFWIGPLVGAIVASLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
10.1093/oxfordjournals.molbev.a025772
RefSeq
NP_001094669.1